AMERICAN REGENT LABORATORIES INC SUB OF LITPOLD PH -- METHYLENE BLUE INJECTION  -- 6505-01-181-1734
<pre>=====================  Product Identification  =====================

Product ID:METHYLENE BLUE INJECTION
MSDS Date:04/24/1992
FSC:6505
NIIN:01-181-1734
=== Responsible Party ===
Company Name:AMERICAN REGENT LABORATORIES INC SUB OF LITPOLD PH
Address:1 LUITPOLD DR
City:SHIRLEY
State:NY
ZIP:11967
Country:US
Info Phone Num:516-924-4000
Emergency Phone Num:800-645-1706
Preparer's Name:JOHN PURPURA
CAGE:32288
=== Contractor Identification ===
Company Name:AMERICAN REGENT - LUITPOLD PHARMACEUTICALS INC
Address:1 LUITPOLD DR
Box:City:SHIRLEY
State:NY
ZIP:11967-5000
Country:US
Phone:516-924-4000/800-645-1706
CAGE:32288

=============  Composition/Information on Ingredients  =============

Ingred Name:METHYLENE BLUE
CAS:61-73-4
RTECS #:SO5600000
Other REC Limits:NONE RECOMMENDED

Ingred Name:WATER
CAS:7732-18-5
RTECS #:ZC0110000
Other REC Limits:NONE RECOMMENDED

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:NONE SPECIFIED BY MANUFACTURER.
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:POSSIBLE ALLERGIC REACTION TO FUMES IF
    INHALED,INGESTED OR IN CONTACT W/SKIN.EYE/SKIN &/OR RESPIRATORY
    TRACT IRRIT.POSSIBLE HYPERSENSITIZATION.
Explanation of Carcinogenicity:PER MSDS:CHEMICAL LISTING OF
    CARCINOGEN:NTP/IARC/OSHA:NO.
Effects of Overexposure:POSSIBLE ALLERGIC REACTION TO FUMES IF
    INHALED,INGESTED OR IN CONTACT W/SKIN.EYE/SKIN &/OR RESPIRATORY
    TRACT IRRIT.POSSIBEL HYPERSENSITIZATION.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

=======================  First Aid Measures  =======================

First Aid:INHAL:REMOVE PERSON TO FRESH AIR.REMOVE CONTAM CLOTHING.SEEK
    MED ATTN.INGEST:FLUSH MOUTH OUT W/WATER.SEEK MED ATTN.SKIN
    CONTACT:REMOVE CONTAM CLOTHING.FLUSH AREA W/WATER.SEEK MED ATTN.EYE
    CONTACT:FLUS H W/WATER.SEEK MED ATTN.FOR ADDITIONAL INFORMATION
    REFER TO THE PRODUCT INSERT.

=====================  Fire Fighting Measures  =====================

Flash Point:NA
Autoignition Temp:Autoignition Temp Text:NP
Lower Limits:NA
Upper Limits:NA
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL, OR FOAM
    AS APPROPRIATE FOR SURROUNDING FIRE & MATERIALS.
Fire Fighting Procedures:FIREFIGHTERS SHOULD USE SELF-CONTAINED
    BREATHING APPARATUS & PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES.

==================  Accidental Release Measures  ==================

Spill Release Procedures:WEAR RECOMMENDED PERSONAL PROTECTIVE
    EQPMT.VACUUM SPILLAGE W/VACUUM CLEANER HAVING HIGH EFFICIENCY
    PARTICULATE(HEPA)FILGER OR ABSORB LIQUID W/PAPER TOWELS.WIPE
    WORKING SURFACES TO DRYNESS, THEN WASH W /SOAP/WATER.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

======================	Handling and Storage  ======================

Handling and Storage Precautions:AS GENERAL RULE WHEN HNDLG
    PHARMACEUTICAL PRODUCTS AVOID ALL COTNACT & INHAL OF
    DUST/FUMES/MISTS &/OR VAPORS ASSOC W/PRODUCT.DONT MIX W/OTHER
    DRUGS.
Other Precautions:METHYLENE BLUE USP 1% IS STERILE SOLUTION OF
    METHYLENE BLUE IN WATER FOR INJECTION W/PH OF 3.0-4.5.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:NA; HOWEVER NIOSH APPROVED RESPIRATOR SHOULD BE
    AVAILABLE.
Ventilation:LOCAL EXHAUST RECOMMENDED.
Protective Gloves:DISPOSABLE SURGICAL LATEX GLOVES
Eye Protection:SAFETY GOGGLES
Other Protective Equipment:DISPOSABLE PROTECTIVE APPAREL(PROTECT
    EXPOSED SKIN).
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health

==================  Physical/Chemical Properties  ==================

HCC:N1
Boiling Pt:B.P. Text:NA
Melt/Freeze Pt:M.P/F.P Text:NP
Decomp Temp:Decomp Text:NP
Vapor Pres:NA
Vapor Density:NA
Spec Gravity:NP
pH:3-4.5
Viscosity:NP
Evaporation Rate &amp; Reference:NP
Solubility in Water:SOLUBLE
Appearance and Odor:DEEP BLUE SOLUTION, RELATIVELY ODORLESS
Percent Volatiles by Volume:NP
Corrosion Rate:NP

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:DO NOT MIX W/OTHER DRUGS.
Hazardous Decomposition Products:METHYLENE BLUE EMITS TOXIC FUMES WHEN
    HEATED TO DECOMPOSITION.

====================  Disposal Considerations  ====================

Waste Disposal Methods:THOUGH NOT EPA REGULATED, WASTE SHOULD BE
    DISPOSED OF IN ACCORDANCE WITH LOCAL, STATE AND FEDERAL
    REGULATIONS.DONT MIX W/OTHER SUBSTANCES.

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